AWARD NUMBER: W81XWH-15-1-0420 TITLE: Cellular Energy Pathways as Novel Targets for the Therapy of Autosomal Dominant Polycystic Kidney Disease PRINCIPAL INVESTIGATOR:

AWARD NUMBER: W81XWH-15-1-0419 TITLE: Cellular Energy Pathways as Novel Targets for the Therapy of Autosomal Dominant Polycystic Kidney Disease PRINCIPAL INVESTIGATOR:

AWARD NUMBER: W81XWH-14-1-0464 TITLE: The Roles of Primary Cilia in Cardiovascular System PRINCIPAL INVESTIGATOR:

Primary cilia are sensory organelles that extend from the cell surface and senseextracellular signals. Endothelial primary cilia protruding from the inner surface of blood vessel wallssense changes in blood flow and convert this mechanosensation into an intracellular biochemical/molecular signal, which triggers a cellular response. Primary endothelial cilia dysfunction maycontri...

AWARD NUMBER: W81XWH-14-1-0219 TITLE: Novel Molecular Targets for kRAS Downregulation: Promoter G-Quadruplexes PRINCIPAL INVESTIGATOR: CONTRACTING ORGANIZATION: REPORT

Fasting in a 16-year-old girl at-risk of autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of inherited kidney disease that results in renal failure. PKD currently has no causative therapy. However, some treatment options are available, ranging from symptomatic therapy to delaying the onset of end-stage renal failure. Early diagnosis of adult polycystic kidney disease is vital in order to prevent its complic...

AWARD NUMBER: W81XWH-14-1-0551 TITLE: Targeting Siah2 as Novel Therapy for Metastatic Prostate Cancer PRINCIPAL INVESTIGATOR: